The authors of this CAST Issue Paper examine the current plant protection revolution that is driven by the biological realities of pesticide resistance, various market forces, and real or perceived side effects of pesticides. They point out that “crop protection chemicals have been miraculous, but their automatic use is no longer efficacious or justifiable.” Led by Task Force Chair Susan T. Ratcliffe, the authors of this paper consider new technologies such as drones, smart sprayers, and specially designed cultivators–and they examine current biotech advancements such as CRISPR-Cas9 and other techniques that may fit well into integrated systems. They emphasize the need for research, communication, and collaboration as scientists “develop integrated strategies for managing pests while preserving ecosystem services and farm productivity.” The paper can be downloaded from here.